Hesl Defends Normal Hematopoietic Stem Cells Against T Cell Leukemic Environment

摘要：

　　Objective In T-ALL leukemia mouse model,the impacts of leukemic environment on normal HSC and HPC were distinct in that normal HSCs were preserved in part because of increased mitotic quiescence of HSCs and resulted exhaustion of HPC proliferation.Our current work is to further explore the molecular mechanism of leukemic environment on normal HSCs.

作者: Tian Chen Li Qiao Cao Zhipan Zheng Guo-guang Yuan Wei-ping Cheng Tao

作者单位: Department of Hematology,Tianjin Medical University Cancer Institute and Hospital State Key Laboratory of Experimental Hematology,Institute of Hematology and Blood Diseases Hospital,

会议类型: 国内会议

会议名称: 肿瘤多学科综合诊治新进展学术研讨会

会议地点: 三亚

会议语种:英文

页码: 151-152

在线出版日期: 2012-11-16（万方平台首次上网日期，不代表论文的发表时间）