Wnt/β-catenin Pathway Forms a Negative Feedback Loop during TGF-β1 Induced Human Normal Skin Fibroblast-to-Myofibroblast Transition

摘要：

　　Background Fibroblast-to-myofibroblast transition is a key event during wound healing and hypertrophic scar formation.Previous studies suggested Wnt/β-catenin signaling might be involved in the wound healing.However,its specific role in skin fibroblast-to-myofibroblast transition remains unclear.Objective To investigate the specific role of β-catenin during the transforming growth factor-β1 induced normal skin myofibroblast transition.

作者: Jiaqi Liu Yunchuan Wang Qing Pan ZhanfengZhang Juntao Han Xiongxiang Zhu Chaowu Tang Dahai Hua

作者单位: Department of Burns and Cutaneous Surgery, Xijing Hospital, The Fourth Military Medical University, Outpatient Department, The SecondArtillery Engineering College, 18 Lishan Road, Xi ”an, Shaanxi 7100

会议类型: 国内会议

会议名称: 第八届全国创伤修复(愈合)与组织再生学术交流会

会议地点: 广州

会议语种:英文

页码: 446-447

在线出版日期: 2012-08-30（万方平台首次上网日期，不代表论文的发表时间）