Psycholonogy Condition and Autonomic Dysfunction in IBS
As the primary link between brain and gut,autonomic dysfunction play a role in the pathophysiology of IBS.The aim of this study was to assess autonomic response to cold-water test and colon distension.Method:30 women with IBS and 20 healthy women participated.HAMA and HAMD were used to measure their anxiety and depression conditions.5-minite-short-time heart rate variability(HRV) spectral analysis were aseessed at baseline and after a cold-water test,just before and after a colon distention.Results:IBS-group showed a higher score in HAMA and HAMD(p<0.01) and showed a significant increase in the low frequecy band/high frequency(L/H) band ratio and a decrease in the high frequncy band power during the period just before and after colon distension(p<0.01 ),which was significantly different from controls.Conclusions:These findings support the notion that an abnormal autonomic nerverse activities responsing to visceral and psychological stimuli may play a role in the pathophysiolgy of IBS.
IBS psycholonogy autonomic nerverse function stress heart rate viriability
Wan Hongyu Chen Yulong
Department of Gastrointerrology, Songjiang District Center Hospital, Shang Hai, China Department of Gastrointerrology, the First affiliated Hospital of Zhengzhou University, Zhengzhou 45
国内会议
北京
英文
204-204
2010-09-10（万方平台首次上网日期，不代表论文的发表时间）