Association of polymorphisms in angiotensin converting enzyme and nitric oxide synthase 3 genes with high-altitude pulmonary edema:A case-control study and meta-analysis
Background:Over the past few decades,there has been a steady increase in work-related travel to mountain and high plain regions; this pattern of transient migration has been accompanied by a concomitant increase in high-altitude pulmonary edema (HAPE).Studies of HAPE have suggested a genetic component to susceptibility and implicated the angiotensin converting enzyme (ACE) gene of the renin-angiotensin-aldosterone-system pathway and the nitric oxide synthase 3 (NOS3) gene of the NO pathway in HAPE development.This study was designed to assess whether genetic variants in the ACE and NOS3 genes are associated with HAPE risk.
王清青 黄岚 覃军 吴国明 李黔宁 李亚斐 熊鸿燕 于磊 黄国荣 张路 刘雅琼 王太武 林辉 任谦 刘平
重庆市第三军医大学军事预防医学院流行病学教研室 重庆市第三军医大学新桥医院 青海省格尔木市中国人民解放军第22医院
国内会议
第十二届中华医学会临床流行病学学术会议暨第六届世界中医药学会联合会临床疗效评价学术交流会
北京
英文
72-73
2012-11-01（万方平台首次上网日期，不代表论文的发表时间）