Flavonoid compounds from litchi (Litchi chinensis Sonn.) seeds and appraisal of their α-glucosidase inhibitory activities (Ⅱ)
Using a bioactivity-guided method,two new flavanone glycosides and eight previously reported flavonoids were isolated from an aqueous ethanol (50%) extract of litchi (Litchi chinensis Sonn.) seeds.By spectroscopic methods,including 1D and 2D NMR (heteronuclear multiple quantum coherence (HMQC),heteronuclear multiple bond correlation (HMBC)) techniques and mass spectrometry,the chemical structure of the new compounds were elucidated as (2R)-pinocembrin-7-O-”(2”,6”-di-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside” (1),pinocembrin-7-O-(6”-O-α-L-arabinose-β-D-glucopyranoside) (2),and the eight known compounds were determined to be quercetin (3),phlorhizin (4),pinocembrin-7-O-glucoside (5),kaempferol-7-O-β-D-glucopyranoside(6),onychin (7),nairutin (8),narcissin (9) and pinocembrin-7-O-”(6”-O-β-D-glucopyranoside)-β-D-glucopyranoside) (10).Some of the isolated flavonoids were tested for their inhibitory effects on α-glucosidase; compounds 3 and 4 showed stronger inhibition than the control,acarbose.
litchi seeds flavonoid compounds α-glucosidase inhibitory activity
Shen Ren Duoduo Xu Yang Gao Zhi Pan Yuting Ma Ruizhi Jiang Qipin Gao
Research andDevelopment Center, Changchun University of Traditional Chinese Medicine,Changchun130117 Research andDevelopment Center, Changchun University of Traditional Chinese Medicine,Changchun130117
国内会议
海口
英文
91-91
2012-11-01（万方平台首次上网日期，不代表论文的发表时间）