Ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry based chemical profiling approach to rapidly reveal chemical transformation of sulfur-fumigated medicinal herbs, a case study on white ginseng

摘要：

　　Sulfur-fumigation may induce chemical transformation of medicinal herbs.Development of rapid method to reveal potential sulfur-fumigation induced chemical transformation of herbs is a very important issue for efficacy and safety of herb application.In present study,a new strategy was proposed to rapidly reveal chemical transformation of sulfur-fumigated herbs by ultra-high-performance liquid chromatography-quadrupole/time of flight mass spectrometry (UHPLC-QTOF-MS/MS) based chemical profiling approach.

关键词： UHPLC-QTOF-MS/MS Ginseng Ginsenoside Chemical transformation Sulfur-fumigation

作者: Song-Lin Li Shi-Lin Chen Hong-Xi Xu Hong Shen Ling-Ying Zhu Jun Xu Xiao-Bin Jia Hong-Mei Zhang Ge Lin Hao Cai Bao-Chang Cai

作者单位: Department of Metabolomics and Key Laboratory of New Drug Delivery System of Chinese Materia Medica, The Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences & Peking Union Med School of Chinese Medicines, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, P School of Biomedical Sciences, The Chinese University of Hong Kong, Hong Kong SAR, PR China Nanjing Haichang Chinese Medicine Co.Lit.and Nanjing University of Chinese Medicine,Nanjing 210029,

会议类型: 国内会议

会议名称: 中药与天然药高峰论坛暨第十二届全国中药和天然药物学术研讨会

会议地点: 海口

会议语种:英文

页码: 130-131

在线出版日期: 2012-11-01（万方平台首次上网日期，不代表论文的发表时间）