Metabolic engineering and profiling of rice with increased lysine
Lysine (Lys) is the first limiting essential amino acid in rice which is a stable food for half of the world population.Efforts,including genetic engineering approach,thus far have not achieved a desirable level of Lys in rice.In this study,we engineered rice for increased Lys through expressing the bacterial Lys feedback-insensitive aspartate kinase (AK) and dihydrodipicolinate synthase (DHPS) genes to enhance Lys biosynthesis; through RNA interference of rice bifunetional lysine ketoglutaric acid reductase/saccharopine dehydropine dehydrogenase (LKR/SDH) gene to down-regulate Its catabolism; andby combined expression of bacterial AK and DHPS and interference of LKR/SDH genes to achieve both metabolic effects.
Qiaoquan Liu Xiaohang Long Qing Wang Minghong Gu Samuel S. M. Sun
Key Laboratory of Plant Functional Genomics of the Ministry of Education, College of Agriculture, Ya State Key Laboratory of Agrobiotechnology, School of Life Sciences, The Chinese University of Hong K
国内会议
南昌
英文
30-30
2012-10-01（万方平台首次上网日期，不代表论文的发表时间）