Sansanmycin H-S, antimycobacterial uridyl peptide from Streptomyces sp.SS

摘要：

　　Streptomyces sp.SS is a producer ofsansanmycins.Further investations of this strain led to isolation and structural elucidation of twelve new uridyl peptides,Sansanmycin H-S (1-12).Three of them bear tryptophan as C-terminal amino acid and four of them have phenylalanine in the place of Methionine,Leucine and Alanine,which both were found here for the first time in uridyl peptide antibiotics.The different amino acids in those seven compounds indicate the different adenylation domain activity of Streptomyces sp.SS from other uridyl peptides producers.

作者: Yunying Xie Hongzhang Xu Ying Yu Ruxian Chen

作者单位: Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College

会议类型: 国内会议

会议名称: 第四届全国微生物资源学术暨国家微生物资源平台运行服务研讨会

会议地点: 成都

会议语种:英文

页码: 59-59

在线出版日期: 2012-11-23（万方平台首次上网日期，不代表论文的发表时间）