Involvement of prostaglandin E receptor EP2 in paeoniflorin-induced human hepatoma cells apoptosis

摘要：

　　Objective:Prostaglandin E2 (PGE2) has been shown to play important roles in several aspects of tumor development and progression.PGE2 mediated its biological activity through binding to the four prostanoid receptors EP1 through EP4.The present study was designed to investigate the role of EP2 receptor in the proliferation and apoptosis of human hepatocellular carcinoma cell lines HepG2,SMMC-7721 and the effect of paeoniflorin,a monoterpene glucoside.

作者: Wuyi Sun Shanshan Hu Qingtong Wang Jingyu Chen Huaxun Wu Wei Wei

作者单位: Institute of Clinical Pharmacology, Anhui Medical University, Key Laboratory of Anti-inflammatory and Immunopharmacology, Ministry of Education, Hefei, Anhui Province, China 230032

会议类型: 国内会议

会议名称: 第十三次全国临床药理学学术大会

会议地点: 成都

会议语种:英文

页码: 99-99

在线出版日期: 2012-10-26（万方平台首次上网日期，不代表论文的发表时间）