Hedgehog Signaling Pathway and Ovarian Cancer

摘要：

　　Epithelial ovarian carcinoma (EOC) is the most common form of ovarian malignancies and the most lethal gynecologic malignancy in the United States.To date,in spite of treatment to it with the extensive surgical debulking and chemotherapy,the prognosis of EOC remains dismal.Recently,it has become increasingly clear that in many instances,the signaling and molecular players that control development are the same,and when inappropriately regulated,drive tumorigenesis and cancer development.Here,we discuss the possible involvement of Hedgehog(Hh) pathway in the cellular regulation and development of cancer in the ovaries.

关键词： Hedgehog signaling ovarian cancer targeted therapy

作者: Qi Chen Guolan Gao Shiwen Luo

作者单位: Department of Obstetric and Gynecology,The Second Affiliated Hospital of Nanchang University,Nanchan Department of Obstetric and Gynecology,General Hospital of Beijing Aeronautics,Beijing,100012,China Center for Experimental Medicine,The First Affiliated Hospital of Nanchang University,Nanchang,33000

会议类型: 国内会议

会议名称: 第八届全国中西医结合妇产科学术大会

会议地点: 重庆

会议语种:英文

页码: 341-342

在线出版日期: 2012-10-13（万方平台首次上网日期，不代表论文的发表时间）