SCAP gene polymorphisms decrease the risk of non-alcoholic fatty liver disease in female metabolic syndrome subjectsr

摘要：

　　The prevalence of Nonalcoholic fatty liver disease(NAFLD) in metabolic syndrome(MS) population is much higher than that in non-MS,NAFLD is recognized as the hepatic additional and specific manifestation of MS.Common variants in the human SREBF-1,SREBF-2 and SCAP genes have been demonstrated to associate with dyslipidemia,meanwhile metabolism of cholesterol and fatty acids plays an important role in the pathogenesis of NAFLD,so we hypothesized that some variants in these genes may be associated with NAFLD.

关键词： genetic polymorphism Nonalcoholic fatty liver disease,SCAP

作者: Shanshan Sun Miao Wang Haiyan Song Tao Wu Huafeng Wei Songhua He Zhaoguo Ding Guang Ji

作者单位: Institute of Digestive Disease,Longhua Hospital Shanghai University of Traditional Chinese Medicine, Institute of Digestive Disease,Longhua Hospital Shanghai University of Traditional Chinese Medicine, Institute of Digestive Disease,Longhua Hospital Shanghai University of Traditional Chinese Medicine, Department of Internal medicine of traditional Chinese Medicine,Longhua Hospital Shanghai University Department of Statistics,Uppsala University,Uppsala ,Sweden Institute of Digestive Disease,Longhua Hospital Shanghai University of Traditional Chinese Medicine,

会议类型: 国内会议

会议名称: 第二十一次全国中西医结合肝病学术会议

会议地点: 昆明

会议语种:英文

页码: 209-210

在线出版日期: 2012-08-01（万方平台首次上网日期，不代表论文的发表时间）