Evaluation of cardiopulmonary effects of total intravenous anesthesia using a drug combination of medetomidine,lidocaine,butorphanol and propofol (MLBP-TIVA) with or without controlled ventilation and effect of positioning in mechanically ventilated horse
The purpose of this study was to evaluate cardiopulmonary effects of MLBP-TIVA with or without controlled ventilation in horses and to determine effects of positioning on cardiovascular function in mechanically ventilated horses.Five healthy adult horses were anesthetized with MLBP-TIVA for 2-hours on 3-occasions at 4-week interval with (CMV-group) or without controlled mechanical ventilation(SB-group) and in lateral(LR-group) or dorsal(DR-group) recumbency.Anesthesia was induced with lidocaine(1 mg/kg:Ⅳ) and propofol(3 mg/kg:Ⅳ) following premedications with medetomidine(0.005 mg/kg:Ⅳ) and butorphanol(0.02 mg/kg:IV),and then maintained by propofol infusion combined with constant rate infusions of medetomidine(0.0035 mg/kg/h),lidocaine(3 mg/kg/h) and butorphanol(0.024 mg/kg/h).Data were compared between groups using repeated-measures ANOVA.The level of significance was set at P＜0.05.
butorphanol cardiopulmonary effects horses lidocaine medetomidine propofol TIVA
Ishizuka T Nagaro T Sudo K Itami T Tamura J Fukui S Miyoshi K Yamashita K
Rakuno Gakuen University,Ebetsu,Hokkaido 069-8501,Japan Rakuno Gakuen University,Eb
国内会议
第二届亚洲兽医外科学大会暨第19次中国畜牧兽医学会兽医外科学分会学术研讨会
南京
英文
35-35
2012-11-01（万方平台首次上网日期，不代表论文的发表时间）