Ethyl acetate fraction of cynanchum peniculatum and bee venom therapy in experimental canine stifle osteoarthritis

摘要：

This study evaluated the therapeutic effects of the phytomedicine,ethyl acetate fraction of the Cynanchum peniculatum(EACP) and bee venom(BV) of the honey bee(Apis mellifera) for the treatment of experimental stifle osteoarthritis(OA) in 24 skeletally mature mixed small breed dogs(age 2 to 6 years,weight 2.8 to 9 kg).One year after induction of OA,the animals were randomly allocated in 2 groups;the EACP-group received 10％ solution of EACP 0.5 mL plus 0.2 mL lidocaine;and the BV-group received 10％ solution of BV 0.5 mL plus 0.2 mL lidocaine intraarticularly twice in a week in the OA-induced stifles for one month.The joint tissue specimens,synovial fluid(SF) and blood samples were collected prior to and 12 months after induction of OA,and one month posttreatment.

关键词： osteoarthritis Cynanchum peniculatum Bee venom TRAP TIMP-2 gog

作者: Hae Beom Lee Min Su Kim Ki Chang Lee Md.Rafiqul Alam

作者单位: Department of Surgery,College of Veterinary Medicin and Bio-Safety Research Institute,Chonbuk Nation Department of Surgery and Obstetrics,Fa

会议类型: 国内会议

会议名称: 第二届亚洲兽医外科学大会暨第19次中国畜牧兽医学会兽医外科学分会学术研讨会

会议地点: 南京

会议语种:英文

页码: 40-40

在线出版日期: 2012-11-01（万方平台首次上网日期，不代表论文的发表时间）