Ultrastructural identification of different subtypes of interstitial cells of Cajal in the chicken ileum
Ultrastructural characteristics of different subtypes of interstitial cells of Cajal (ICC) remain unclear in birds however birds have significant economical and scientific notability.Our aim was describe and classify ICC in the chicken gut.Material and Methods:The ileum of normal adult three-yellow broiler chickens (n=10) were studied by transmission electron microscopy (TEM).Results:ICC were spindle or stellate shaped with ramified cell processes.They had numerous mitochondria,abundant intermediate filaments,fusiform nuclei (oval or indented),with a dense band of peripheral heterochromatin and formed close contacts by true gap junctions with each other and with neighbouring smooth muscle cells (SMC).They were in close contact with enteric nerves,but true gap junctions were not found between them.A new subtype of ICC located in the lamina propria mucosae has been discovered.Some of the ICC showed typical features of SMC including a basal lamina,caveolae and dense bodies.Lacking intermediate filaments and caveolae distinguished them from the fibroblast-like cells (FLC) showing well-developed secretory organelles,including coated vesicles,a patchy basal lamina.Conclusion:The ultrastructural features and distribution of ICC in chicken intestine is similar to mammals.They may play similar key regulatory roles in gastrointestinal motility.The new subtype of ICC discovered in the lamina propria mucosae may play role in the regulation of secretion and absorption.
Chicken ileum Interstitial cells of Cajal (ICC) Transmission electron microscopy (TEM)
Ping Yang Jameel Ahrned Gandahi Xunguang Bian Li Wu
Laboratory of Animal Histology and Embryology, College of Veterinary Medicine, Nanjing Agricultural Laboratory of Animal Histology and
国内会议
中国畜牧兽医学会动物解剖学及组织胚胎学分会第十七次学术研讨会
山西太谷
英文
52-62
2012-07-01（万方平台首次上网日期，不代表论文的发表时间）