49.Diffusion tensor imaging for predicting the clinical outcome of delayed encephalopathy of acute carbon monoxide poisoning
Objective The aim of the present study was to determine the relationship between neuropsychiatric outcomes and diffusion tensor imaging (DTI) in patients with delayed encephalopathy after acute carbon monoxide poisoning (DEACMP).Methods and Materials 66 patients and 60 healthy controls were included in this study.Median fractional anisotropy (FA) of the white matter bilaterally was compared between patients and healthy controls.The Glasgow outcome scale (GOS) was assessed at four to six months following DEACMP.The association between the GOS score and FA variables was explored using the Spearman rank correlation.Results The FA values in white matter were reduced in patients with DEACMP compared with those in the volunteers.Of the 66 patients,21 (31.8％) achieved a good outcome (GOS-5),26 (36.4％) had moderate disability (GOS-4),14 (21.2％) had severe disability (GOS-3),5 (7.6％) were in a vegetative state (GOS-2),and none of the patients died (GOS-1).The FA values in the white matter in patients with DEACMP correlated significantly with GOS.Conclusion DTI may be a valuable tool for assessing the severity of tissue injury and may be a predictor of outcome.
Carbon monoxide poisoning Delayed encephalopathy after CO poisoning Diffusion tensor imaging
侯晓敏 马琳琳 武连华 张奕 葛环 李茁 高宇 周立荣 高春锦
首都医科大学附属北京朝阳医院高压氧科 首都医科大学附属北京朝阳医院放射科
国内会议
合肥
英文
141-147
2012-10-01（万方平台首次上网日期，不代表论文的发表时间）