Effect of Oxymatrine on TGF-β/Smad Signaling Pathway in Human Keloid Fibroblasts

摘要：

Objective To study the mechanism of the suppression of oxymatrine on collagen synthesis of human keloid fibroblasts.Metholds Human keloid fibroblasts were cultured as an experimental model.The effect of oxymatrine on TGF-β/Smad signaling pathway were analyzed by Western Blot.Meanwhile,the mRNA of positive molecule were analyzed by RT-PCR.ResultsThe expression of TGF-β1,TβRI,TβRII,Smad4,Smad7 were insignificant compared to control group.

作者: Fan Dongliang Guo Shu Liu Jinchao Wang Yuxin

作者单位: Department of plastic surgery, First affiliated hospital of China medical university,Shenyang 110001 Shenyang Friendship Plastic & Cosmetic Hospital,Shenyang 110014, China

会议类型: 国内会议

会议名称: 第三届全球华裔整形外科医师大会

会议地点: 西安

会议语种:英文

页码: 108-108

在线出版日期: 2012-10-12（万方平台首次上网日期，不代表论文的发表时间）