Observation on effect of treating diabetic foot ulcers in rats by transplanting with bone-marrow derived mesenchymal stem cells in different ways
Objective:To assess the therapeutic effect of treating diabetic foot ulcers (DFUs) in rats by transplanting subcutaneously around the wounds and intramuscularly into the leg with bone marrow derived mesenchymal stem cells (BM-MSCs).Methods:BM-MSCs from male Wistar rats were cultured by the whole bone marrow adherence method until the third generation.Then BM-MSCs were labeled by 4,6-diamino-2-phenylindole (DAPI) in vitro.
Bone-marrow derived mesenchymal stem cells Diabetic foot Wound healing Vascular endothelial growth factor
WAN Jiangbo CAI Qian LIU Yi
Center of Military Burns and Plastic Surgery, Lanzhou General Hospital of Lanzhou Military Command of Chinese PLA.Lanzhou 730050, Gansu, China
国内会议
西安
英文
139-140
2012-10-12(万方平台首次上网日期,不代表论文的发表时间)