Comparative proteome analysis to explore molecular changes mediated by M2 muscarinic receptor with C176W mutation

摘要：

Objectives We had reported a missense mutation(C176W)in the M2-muscarinic acetylcholine receptor (CHRM2)gene associated with familial dilated cardiomyopathy.However,the exact molecular mechanisms by which the C176W mutation contributes to familial DCM was still unclear.Our aim was to identify differential proteins related to cadiac dysfunction activated via M2 muscarinic receptor with C176W mutation.

作者: Ying Chen Lin Zhang Guiling Ma Dongyan Hou

作者单位: Chaoyang Hospital Affiliated to Capital Medical University,Beijing 100020,China

会议类型: 国内会议

会议名称: 第14届中国南方国际心血管病学术会议

会议地点: 广州

会议语种:英文

页码: 142-142

在线出版日期: 2012-04-11（万方平台首次上网日期，不代表论文的发表时间）