Synergistic effect of pyridoxamine and telmisartan on proliferation,apoptosis and fibrogenic factors expression in human proximal tubular epithelial cells
Objectives Pyridoxamine is one of the deviates of Vitamin B6 which can effectively inhibit the formation of advanced glycation end products(AGEs).Telmisartan is one of the strongest Angiotensin Ⅱ receptor blockers(ARBs).It has been reported that the combined use of pyridoxamine and telmisartan has renoprotective effect on hypertensive renal injury in vivo,but its mechanism is still elusive.
Pengli Zhu Yin Yuan Huizhen Yu Fan Lin
Fujian Provincial Hospital,Fujian Institute of Clinical Geriatrics,Provincial Clinical College,Fujian Medical University,Fuzhou 35001,China
国内会议
广州
英文
253-253
2012-04-11(万方平台首次上网日期,不代表论文的发表时间)