Effection of A CE2/ACE axis on cardiac remodeling in a rat model of myocardial infarction-induced(MI)ischemic heart failure

摘要：

Objectives There is evidence that the Angiotensin-converting enzyme 2(ACE2)can counterbalances ACE by breakdown of angiotensin(Ang)Ⅱ and formation of Ang(1-7).To assess the cardioprotection in the post-myocardial infarction(MI)heart,we treated adult male Sprague-Dawley rats with DIZE,a selective ACE2 inhibitor,and with captopril,an Angiotensin-converting enzyme inhibitor(A-CEI),after permanent coronary artery ligation or sham operation.

作者: Qingzhou Yao Heping Lei Yongheng Fu Mengzhen Zhang Xiyong Yu

作者单位: Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510010,China

会议类型: 国内会议

会议名称: 第14届中国南方国际心血管病学术会议

会议地点: 广州

会议语种:英文

页码: 272-272

在线出版日期: 2012-04-11（万方平台首次上网日期，不代表论文的发表时间）