Involvement of Src and PKC in the expression of Macrophage migration inhibitory factor induced by hydrogen peroxide in HL-1 cells
Background and Objectives Macrophage migration inhibitory factor(MIF),a pleiotropic cytokine plays an important role in the pathogenesis of atrial fibrillation(AF).But the upstream regulation of MIF in atrium myocytes remains unclear.In the present study,we investigated whether and how MIF is regulated in response to the renin-angiotensin system(RAS)and oxidative stress in HL-1 cells.
Fang Rao Chunyu Denng Shulin Wu Xiyong Yu Dingzhang Xiao Sujuan Kuang Qiuxiong Lin Zhixin Shan Jiening Zhu
Department of Cardiology,Guangdong Cardiovascular Institute,Guangdong General Hospital,Guangdong Academy of Medical Sciences,Guangzhou 510080,China
国内会议
广州
英文
274-275
2012-04-11(万方平台首次上网日期,不代表论文的发表时间)