The influence of donor antigenic specificity regulatory T cells exert to B cell”s function of mice after heatr transplantation in mice
Objective To study the influence of donor antigenic specificity CD4+CD25+ regulatory T cells exert to B cell”s function of mice after heart transplantation in mice.Methods We first established heart transplantation model in mice,Balb/c mice as donor,C57bl/6 mice as recipient.The day before the operation and the day after two weeks of the operation,donor antigenic specificity CD4+CD25+regulatory T cells(1 × 106) was injected to the recipient by caudal vein.After one month,we drew the peripheral blood of recipient mice,isolated B cells,and detected the proliferation level of B cells under the stimulation of IgM antibody.The level of IgG and IgA in the peripheral blood of recipient mice was detected too.
XIAO Ya HUANG Chi-bing WANG,Ping-xian
Department Two of Urology,Xinqiao Hospital,Chongqing 400037,China
国内会议
成都
英文
206-207
2011-06-17（万方平台首次上网日期，不代表论文的发表时间）