The Use of Anti-VDAC2 Antibody for the Combined Assessment of Human Sperm Acrosome Integrity and Ionophore A23187-Induced Acrosome Reaction

摘要：

Voltage-dependent anion channel (VDAC) is mainly located in the mitochondrial outer membrane and participates in many biological processes.In mammals,three VDAC subtypes (VDAC1,2 and 3) have been identified.Although VDAC has been extensively studied in various tissues and cells,there is little knowledge about the distribution and function of VDAC in male mammalian reproductive system.Several studies have demonstrated that VDAC exists in mammalian spermatozoa and is implicated in spermatogenesis,sperm maturation,motility and fertilization.However,there is no knowledge about the respective localization and function of three VDAC subtypes in human spermatozoa.

作者: Bianjiang Liu Peng Wang Zengjun Wang Wei Zhang

作者单位: Department of Urology,The First Affiliated Hospital of Nanjing Medical University,Nanjing,China

会议类型: 国内会议

会议名称: 中国性学会性医学专业委员会第七次全国性医学学术会议

会议地点: 南京

会议语种:英文

页码: 93-93

在线出版日期: 2011-04-15（万方平台首次上网日期，不代表论文的发表时间）