Suppression of anoikis by SKP2 amplification and overexpression promotes metastasis of esophageal squamous cell carcinoma

摘要：

Purpose Our earlier studies revealed that gain of chromosome 5p was often seen in Esophageal squamous cell carcinoma.The gene of SKP2,located on chromosome 5p13,plays a critical role in cell cycle progression through its control of several cell cycle regulator proteins.The present study aimed to evaluate the amplification and expression status of SKP2 gene and its function in Esophageal squamous cell carcinoma (ESCC).

作者: Xiao-Chun Wang Min Wu Ming-Rong Wang Yu-Peng Wu Bo Ye Yan-Bin Feng Zi-Qiang Zhang XinXu Ya-Ling Han Yan Cai Qi-Min Zhan

作者单位: State Key Laboratory of Molecular Oncology, Cancer Institute(Hospital), Peking Union Medical College Department of Thoracic Surgery, Cancer Hospital, Peking Union Medical College and Chinese Academy of Central Laboratory, Cancer Institute(Hospital), Peking Union Medical College and Chinese Academy of

会议类型: 国内会议

会议名称: 2007全国首届肿瘤并发症的介入治疗学术研讨会

会议地点: 天津

会议语种:英文

页码: 195-195

在线出版日期: 2007-12-14（万方平台首次上网日期，不代表论文的发表时间）