Simple Fabrication of PEG-based Chemical Micropatterns for Neural Network Formation

摘要：

Neural network formation has attracted increasinginterest for applications in neurotoxicology, neurodevelopmentalbiology, and cell-based biosensors which comprise externalmicroelectronic circuits that stimulate and record neural activity.In this paper, we present a simple and efficient method to createa planar PC12 neural network on well-controlled PEG-basedchemical micropatterns which contain a network of regularhexagon units interconnected by microchannels. X-rayphotoelectron spectroscopy, contact angle goniometer andfluorescence microscopy techniques are used to monitor theindividual steps of the patterning process.

关键词： micropatterning surface modification poly(ethyleneglycol) cell adhesion neural network

作者: Ning-Ping Huang Jun-Cai Shi Yan-Yan Wang Hai Yu

作者单位: State Key Laboratory of Bioelectronics,School of Biological Science and Medical Engineering,Southeast University,Nanjing 210096,P.R.China

会议类型: 国内会议

会议名称: 2012上海市研究生学术论坛暨第三届上海交通大学医(理)工研究生学术论坛

会议地点: 上海

会议语种:英文

页码: 1-4

在线出版日期: 2012-08-15（万方平台首次上网日期，不代表论文的发表时间）