Preparation and in vitro evaluation of plasma-sprayed bioactive akermanite coatings

摘要：

Bioactive ceramic coatings on titanium (Ti) alloy play an important role for orthopedic application.In this study, akermanite (Ca2MgSi2O7) bioactive coatings are prepared by plasma sprayingtechnique. The coating mainly contains akermanite crystal phase and portion of amorphous phase.The bonding strength between the coatings and Ti-6Al-4V substrates is around 38.7-42.2 Mpa,which is obviously higher than that of conventional hydroxyapatite (HA) coatings prepared bysame coating method. The prepared akermanite coatings reveal distinct apatite-mineralizationability in simulated body fluid (SBF). Furthermore, akermanite coatings support the attachmentand proliferation of rabbit bone marrow mesenchymal stem cells (BMSCs). The proliferation rateof BMSCs on akermanite coatings is obviously higher than that on HA coatings. The resultssuggest that akermanite coatings on Ti-6Al-4V substrates may be used for preparation oforthopedic implants due to their excellent bonding strength, apatite mineralization ability andcytocompatibility.

关键词： akermanite coating bonding strength simulated body fluid bone marrow stem cells

作者: De-Liang Yi Cheng-Tie Wu Xu-Bing Ma Heng Ji Xue-Bin Zheng Jiang Chang

作者单位: Key Laboratory of Inorganic Coating Materials,Chinese Academy of Science,1295 Dingxi Road,Shanghai 2 Shanghai Institute of Ceramics,Chinese Academy of Science,1295 Dingxi Road,Shanghai 200050,China School of Life Science,East China Normal University,Shanghai 200062,China Key Laboratory of Inorganic Coating Materials,Chinese Academy of Science,1295 Dingxi Road,Shanghai 2

会议类型: 国内会议

会议名称: 2012上海市研究生学术论坛暨第三届上海交通大学医(理)工研究生学术论坛

会议地点: 上海

会议语种:英文

页码: 1-20

在线出版日期: 2012-08-15（万方平台首次上网日期，不代表论文的发表时间）