A noninvasive, remote and precise method for temperature and concentration estimation using magnetic nanoparticles
This study describes an approach for remote measuring of on-site temperature and particleconcentration using magnetic nanoparticles (MNPs) via simulation and also experimentally.The sensor model indicates that under different applied magnetic fields, the magnetizationequation of the MNPs can be discretized to give a higher-order nonlinear equation in twovariables that consequently separates information regarding temperature and particleconcentration. As a result, on-site tissue temperature or nanoparticle concentration can bedetermined using remote detection of the magnetization. In order to address key issues in thehigher-order equation we propose a new solution method of the first-order model from theperspective of the generalized inverse matrix. Simulations for solving the equation, as well asto optimize the solution of higher equations, were carried out. In the final section we describea prototype experiment used to investigate the measurement of the temperature in which weused a superconducting magnetometer and commercial MNPs. The overall error after ninerepeated measurements was found to be less than 0.57 K within 310–350 K, with acorresponding root mean square of less than 0.55 K. A linear relationship was also foundbetween the estimated concentration of MNPs and the sample’s mass.
Jing Zhong Wenzhong Liu Zhongzhou Du Paulo C′esar de Morais Qing Xiang Qingguo Xie
Department of Control Science and Engineering,Huazhong University of Science and Technology,Wuhan 43 Department of Control Science and Engineering,Huazhong University of Science and Technology,Wuhan 43 Universidade de Brasilia,Instituto de Fisica,Nucleo de Fisica Aplicada,Brasilia DF 70910-900,Brazil School of Life Science and Technology,Huazhong University of Science and Technology,Wuhan 430074,Peo
国内会议
2012上海市研究生学术论坛暨第三届上海交通大学医(理)工研究生学术论坛
上海
英文
1-10
2012-08-15（万方平台首次上网日期，不代表论文的发表时间）