Modulating DNA condensation by interfacial traction: a 3-dimensional elastic rod model
As a coarse-gained model, a super-thin elastic rod subjected to interfacial interactions is used to investigate thecondensation of DNA in intracellular solution. The interfacial traction between the rod and the solution environment isdetermined in terms of the Young-Laplace equation. The Kirchhoff’s theory of elastic rod is used to analyze theequilibrium configuration of a DNA segment under the action of the interfacial traction. The influences of the interfacialenergy factor and bending stiffness on the toroidal spool formation of the DNA segment are discussed. The results showthat the condensation of DNA is mainly determined by competition between the interfacial energy and elastic strainenergy of the DNA itself, and the interfacial traction is one of forces that drive DNA condensation.
DNA condensation interfacial traction thin elastic rod
黄再兴
南京航空航空大学结构强度研究所,南京210016
国内会议
哈尔滨
英文
1-4
2011-08-22（万方平台首次上网日期，不代表论文的发表时间）