Silver Nanoparticles Enhanced Chemiluminescence of the Luminol–KIO4 System for the Determination of Indapamide by Flow-Injection Analysis
The experiments indicated that silver nanoparticles (AgNPs) could greatly enhance the chemiluminesence intensity of the luminol- KIO4 system in sodium hydroxide media, but indapamide could inhibit the chemiluminesence signals significantly. Based on this inhibitive phenomenon, a flow injection CL method for the determination of indapamide has been established. Under the optimized conditions, the linear range for the determination of indapamide was 1.0×10-9 to 2.0×10-8g/mL (0.9941) and 2.0×10-8 to 1.0×10-7g/mL (0.9978) with a detection limit of 6.0×10-10 g/mL. The relative standard deviations for 11 repeated measurements of 5.0×10-9g/mL and 5.0×10-8g/mL indapamide were 2.1％ and 1.8 ％, respectively. The method has been successfully applied to the determination of indapamide in commercial tablets with recoveries in the range from 97.0％ to 102.0％.
silver nanoparticles chemiluminescence indapamide flow-injection
Hongyan Ma Meng Yang Yuecheng Zhang Juanjuan Luo
Institute of Analytical Chemistry, College of Chemistry and Chemical Engineering, Yan’an University,
国内会议
呼和浩特
英文
75-75
2011-07-20（万方平台首次上网日期，不代表论文的发表时间）