Protective Effects of Hypercapnic Acidosis in an In Vivo Model of Ventilator-induced Lung Injury
Research efforts in the acute respiratory distress syndrome(ARDS) have recently focused on attempts to improve outcome by limiting potential new or worsening lung injury caused by adverse mechanical ventilation strategies. The ARDS Network study has shown improved clinical outcomes using ”low stretch” ventilation strategies that limit tidal volumes and inflation pressures and presumably reduce ventilator-induced lung injury (VILI)”1”. Low tidal volume ventilation is frequently associated with a concomitant respiratory acidosis that, rather than being a side effect to be corrected or tolerated, has been suggested by some to be potentially beneficial”2,3”.
Yunxia Liu Hongyin Du
Tianjin 1st Center Hospital
国内会议
天津
英文
226-235
2009-12-05(万方平台首次上网日期,不代表论文的发表时间)