TGF-β Signaling and Osteoarthritis

摘要：

Osteoarthritis (OA) is a common joint degenerative disease affecting more than 25％ of people over the age of 18. The pathogenesis of OA is poorly understood. Currently there is no effective disease- modifying treatment for OA. Several lines of evidence suggest that the TGF-β/Smad pathway plays a critical role in OA development. However, the downstream target gene(s) for this signaling pathway during OA development remain unknown.

作者: Di Chen

作者单位: Department of Biochemistry, Rush University, Chicago, IL, USA

会议类型: 国内会议

会议名称: 第四届积水潭骨科论坛

会议地点: 北京

会议语种:英文

页码: 93-95

在线出版日期: 2012-04-19（万方平台首次上网日期，不代表论文的发表时间）