Thermodynamic and spectroscopic study on the binding of berberine to herring sperm DNA

摘要：

The interaction of drug molecules with DNA has become an active research area in recent years. Because the intracellular target for a wide range of anticancer and antibiotic drugs is DNA. Berberine is an important traditional medicinal herb, which has been effectively used in the treatment of dysentery, diarrhea, stomatitis, throat infections, and hepatitis in folk medicine. This paper investigates the association of herring sperm DNA (hsDNA) with Berberine (BH) by UV-Vis absorbance spectroscopy and fluorescence spectroscopy approximately under physiological conditions.

作者: Xiao-Ling Li Min Fang E Tang Bing-Qiong Yu Yan-Jun Hu

作者单位: Hubei Key Laboratory of Pollutant Analysis & Reuse Technology, Department of Chemistry,Hubei Normal University, Huangshi 435002

会议类型: 国内会议

会议名称: 中国化学会第三届全国热分析动力学与热动力学学术会议暨江苏省第三届热分析技术研讨会

会议地点: 南京

会议语种:英文

页码: 104-105

在线出版日期: 2011-10-01（万方平台首次上网日期，不代表论文的发表时间）