Assessment of brain oxygen metabolism with MRI
Introduction The brain represents about 2%of the total body weight.but consumes about 20%of the total energy.The energy demand of the brain is met primarily by aerobic metabolism.Therefore,cerebral metabolic rate of oxygen(CMRO2)is all important index of tissue viability and brain function.Many conditions are related to alterations in oxygen metabolism,such as Huntington’S disease,Alzheimer’S disease and normal aging.In addition,quantitative measurement of CMRO2 is useful in understanding normal cerebral physiology during resting state,sleep,brain activation and physiologic challenges.The measurement of CMRO2 is not yet a routine procedure.Currently available techniques for CMRO2 measurement require the infusion/injection/inhalation of exogenous agent.
LU Han-zhang
Advanced lmaging ResearchCenter,University of Texas Southwestern Medical Center,Dallas,Texas,USA
国内会议
第二十届中国国际医用仪器设备展览会暨技术交流会、中放磁共振年会暨国际磁共振研讨会
北京
英文
16-17
2011-08-18(万方平台首次上网日期,不代表论文的发表时间)