Resting-state functional connectivity reflects polysynaptic anatomical pathways

摘要：

Introduction Intrinsic functional connectivity MRI(fcMRI)provides all indirect approach to measure the organization of brain systems．However,all unresolved question is whether functional connectivity measured by resting state fMRI reflects anatomical connections．In the present study we used the well．characterized anatomy of cerebro-ponto·cerebellar pathway to directly test whether functional connectivity is dependent on a specific polysynaptic pathway．Cortical areas project to the contralateral cerebellum via efferents to the pons and then to the cerebellar cortex．Afferents pass through the deep cerebellar nuclei and then the thalamus．These connections are organized as closed，parallel circuits：neocortical areas receive input from the same cerebellar regions that they project to．

作者: LU Jie MA Qing-feng Randy L．Buckner ZHANG Miao CAO Yan-xiang RONG Dong-dong WANG Xiao-yi LI Kun-cheng LIU He-sheng WANG Dang-hong Randy L．Buckner

作者单位: Department of Radiology,Xuanwu Hospital of Capital Medical University Department of Neurology,Xuanwu Hospital of Capital MeScal University Psychology＆Center for Brain Science,Harvard University Departmentof Psychiatry,Massachusetts General Department of adiology,Xuanwu Hospital of Capital Medical University Athinoula A．Martinos Center for Biomedical Imaging,Department of Radiology,Massachusetts General Hos

会议类型: 国内会议

会议名称: 第二十届中国国际医用仪器设备展览会暨技术交流会、中放磁共振年会暨国际磁共振研讨会

会议地点: 北京

会议语种:英文

页码: 61-62

在线出版日期: 2011-08-18（万方平台首次上网日期，不代表论文的发表时间）