长链非编码RNA IncRNA-HEIH通过EZH2蛋白促进肿瘤生长
The human transcriptome comprises not only large numbers of protein-coding messenger RNA(mRNAs) but also a large set of non-protein coding transcripts that have structural，regulatory or unknown functions. Although studies of small non-coding RNAs (18 to 200 nucleotides (nt)) have dominated the field of RNA biology in recent years，a surprisingly wide arcay of cellular functions has also been associated with long non-coding RNAs (1ncRNAs).IncRNA-HEIH is an oncogenic INcRNA that promotes tumor progression and leads us to propose that 1ncRNAs may serve as key regulatory hubs in HCC progression.
hepatocellular carcinoma noncoding RNAs PRC2 IncRNAs cell cycle
杨富 张铃 霍希松 袁继航 徐丹 袁声贤 周伟平 王芳 孙树汉
第二军医大学医学遗传教研室,上海 200433 第二军医大学东方肝胆医院胆道二科,上海200433
国内会议
乌鲁木齐
中文
123-124
2011-07-01（万方平台首次上网日期，不代表论文的发表时间）