抗锌菌Comamonas testosteroniS44锌外排基因研究
A multiple metal(loid)-resistant strain Comamonas testosteroni S44 was isolated from mining waste soil. This bacterium exhibited a high Zn2+ resistant level with a minimal inhibitory concentration (MIC) of 10 mM. To understand the molecular basis for the high zinc resistance，whole genome sequencing was performed and showed large number of genes encoding putative metal(loid) resistance proteins，mobile genetic elements (MGEs)，recent gene transposition，gene duplication and other events pointing to a mobile genome in the process of adaptation to a metal(loid)-contaminated environment. Particularly，a total of nine putative Zn2+ transporters (four putative zntA operons encoding P-type ATPase pumps and five czc operons encoding RND-transport efflux proteins) were identified in the draft genome sequence.
抗锌菌 锌外排基因 移动遗传元件
熊金波 黎航 Susan J．Miller Christopher Rensing 王革娇
华中农业大学农业微生物学国家重点实验室,Wuhan,430070,P.R．of China Biotechnology Computing Facility, Arizona Research Laboratories, The University of Arizona, Tucson,A Department of Soil,Water and Environmental Science, The University of Arizona, Tucson, AZ 85721, USA
国内会议
武汉
中文
29-30
2011-06-01（万方平台首次上网日期，不代表论文的发表时间）