Validation of a gas chromatography-electron capture detection of T-2 and HT-2 toxins in Chinese herbal medicines and related products afterimmunoaffinity column clean-up and pre-column derivatization

摘要：

　　A sensitive, reproducible and accurate gas chromatography-electron capture detection (GC-ECD) method was developed for simultaneous determination of T-2 and HT-2 toxins in Chinese herbal medicines (CHMs) and related products.Then, gas chromatography-mass spectrometry (GC-MS) was applied to confirm the positive results and interfering peaks in some samples.All samples were injected into the Agilent GC-6890N gas system , equipped with a 63Ni electron capture detector on a DB-1701 capillary column (30 m×0.25 mm I.D., 0.25 μm film thickness, Agilent Technologies).

关键词： GC-ECD GC-MS T-2 and HT-2 toxins Chinese herbal medicine Method validation

作者: Kong Weijun Zhang Xiaofei Shen Honghong Ou-Yang Zhen Yang Mei-Hua

作者单位: Institute of Medicinal Plant Development, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China

会议类型: 国内会议

会议名称: 第十一届全国中药和天然药物学术研讨会

会议地点: 沈阳

会议语种:英文

页码: 226

在线出版日期: 2011-10-01（万方平台首次上网日期，不代表论文的发表时间）