The effect of acute and chronic allergen challenge in a new mouse model of allergic asthma

摘要：

　　Background: Existing asthmatic murine models develop tolerance when repetitively exposed to the same allergen. However, patients with asthma are chronically exposed to more than one allergen. Because asthma is a complex multifactorial disease, it is unlikely that an animal model for asthma challenged by a single allergen really reflects all of the morphological and functional features of the chronic human disease.

关键词： 支气管哮喘 动物模型 过敏原

作者: Renping Liu Aiming Meng Qi Hou

作者单位: Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Bei

会议类型: 国内会议

会议名称: 全国第十二届生化与分子药理学学术会议

会议地点: 湖北宜昌

会议语种:英文

页码: 68-69

在线出版日期: 2011-08-19（万方平台首次上网日期，不代表论文的发表时间）