Early Second-Trimester Serum MiRNA Profiling Predict Gestational Diabetes Meilitus

摘要：

To systematically assess whether theseB,lm microRNAs(miRNAs)profiling Call predictgestational diabetes mellitus(GDM)in advante ofthe measurement of blood glucose.Methods We used systematically TaqMan LowDensity Array followed by individual quantitativereverse transcription polymerase chain reactionassays to screen miRNAs in serum which collectedat 16-19 gestational weeks.Logistic regression wasused to estimate the associations between miRNAexpression levels and GDM risk.Results Two miRNAs(miR一29a and miR.222)were identified and consistently validated aseffcient predictors.Taken together.womgn withhigh serum mRNA expression levels hadsignificantly decreased risks of developing GDM

作者: Zhao Chun Dong Jing Pan Shiyang Hu Zhibin Sha Jiahao Xu Junrong Huang Peijun

作者单位: Department of Laboratory Medicine,The First Affiliated Hospital of Nanjing Medical University,Nanjin Department of Epidemiology and Biostatistics, School of public health,Nanjing Medical University,Nan Department of Laboratory Medicine,The First Affiliated Hospital of Nanjing Medical University,Nanjin Laboratory of Reproductive Medicine,Nanjing Medical University,210029 Nanjing,China

会议类型: 国内会议

会议名称: 中华医学第九次全国检验医学学术会议暨中国医院协会临床检验管理专业委员会第六届全国临床检验实验室管理学术会议

会议地点: 北京

会议语种:英文

页码: 176

在线出版日期: 2011-05-24（万方平台首次上网日期，不代表论文的发表时间）