Liver Transplantation Patients treated with Tacrolimus may Induce to Produce Nucleolar Anti-nuclear Antibody
Immunosuppressive drug was used for most allo—liver recipients to prevent graft rejection.Tacrolimus(also known as FK506、is one of the most popular immunosuppressant for transplantation patients. As T lymphocyte specific targeted suppressant， tacrolimus could regulate the immune states of recipients and immune states of patients were hugely different from before transplantation operation The anti-nuclear antibody(ANA)is one of the most important autoantibody against nucleus or/and cytoplasm substance in the imbalance of the immune system，which Can occur in a number of dif.ferent autoimmune disorders including systemic lupus erythematosus and Sjogren’S syndrome，target specific protein antigens present in the body’s nucleated cells.Therefore.we selected liver transplantation patients with a long—term treatment of tacrolimus and control patients with matched liver diseases to detect serum ANA to evaluate the immunity state of allo-liver recipients.
Yongkang Wu Bei Cai Ju Cao Yangjuan Bai Lanlan Wang
Department of Laboratory Medicine,West China Hospital,Sichuan University,Chengdu 610041,P.R.China Department of Laboratory Medicine,the First affiliated Hospital, Chongqing Medical University,Chon
国内会议
中华医学第九次全国检验医学学术会议暨中国医院协会临床检验管理专业委员会第六届全国临床检验实验室管理学术会议
北京
英文
492-493
2011-05-24（万方平台首次上网日期，不代表论文的发表时间）