Determination of Estrogens and Bisphenol A in Bovine Milk by Automated on-line C30 Solid-phase Extraction Coupled with High-performance Liquid Chromatography-mass Spectrometry

摘要：

Using triacontyl bonded silica（C30) as on-line solid-phase extraction（SPE) material and a specially designed online analytical system which allowed large sample volume injection，a high speed and robust online SPE-HPLC-MS method was established for the analysis of five estrogens and bisphenol A（BPA) in milk samples. The milk sample is pretreated with acetonitrile for protein precipitation and then treated with primary secondary amine for the removal of polar impurities in the matrix. Then the pretreated sample can be automatically loaded by a LC pump.

关键词： 键合硅胶 雌激素 液相色谱 牛奶样品

作者: Wei Yan Ying Li Lixia Zhao Jinming Lin

作者单位: State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environme State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environme

会议类型: 国内会议

会议名称: 第五届全国环境化学大会会议

会议地点: 大连

会议语种:英文

页码: 489

在线出版日期: 2008-11-05（万方平台首次上网日期，不代表论文的发表时间）