Effects of Atrazine on Cytochrome P450 Enzymes of Zebrafish (Danio rerio)
In this study,the effects of atrazine(2-chloro-4-ethylamino-6-isopropylamino-1,3,5-triazine) in males and females of adult zebrafish(Danio rerio) were studied. The liver microsomal cytochrome P450 content,NADPH-P450 reductase,aminopyrine N-demethylase(APND),and erythromycin N-demethylase(ERND) activity were measured. Zebrafish were exposed to control and 3 treatments(0.01,0.1,and 1 mg/L) of atrazine for 5,10,15,20,and 25 days. The results indicated that,within the range of test atrazine concentrations,either P450 content or P450 isozyme activities could be induced by atrazine.
阿特拉津 斑马鱼 细胞色素 暴露控制
董晓丽 Lusheng Zhu Jinhua Wang Jun Wang Hui Xie
山东大学资源与环境学院 College of Resources and Environment, Shandong Agriculture University, Taian 271018
国内会议
大连
英文
596
2008-11-05(万方平台首次上网日期,不代表论文的发表时间)