Association Analysis of Porcine Mz1 gene 11bp-deletion Polymorphism with Production Traits
Mx proteins, as interferon-induced GTPases, have been shown to have antiviral activity in different species. Studies in mouse1 and chicken2 showed that allelic isoforms of Mx1 protein have different antiviral activity and also related to chicken leg defects. The porcine Mx1 gene is also polymorphic. Recently it has been recognized that the 11bp-deletion protein is lacking anti-influenza activity in vitro. Genes related to immune response may also have influence on production traits, in this study we detected the allele frequencies of the 11bp-deletion in 6 different porcine breeds and analyzed its association with 7 production traits. No statistical significant associations between the 11bp-deletion mutation and the seven porcine production traits was found inthis study.
生产性状 抗病毒活性 等位基因 免疫反应 基因多态性 缺失突变 养猪技术
Xiangdong Liu Yong Cao Anjing Xiang Mingdi Fang Zengfang Wu Shuhong Zhao
Key Laboratory of Agricultural Animal Genetics,Breeding and Reproduction of Ministry of Education,Hu College of Animal Science,Huanan Agricultural University,Guangzhou 510642,China
国内会议
青岛
英文
221-223
2008-10-18（万方平台首次上网日期，不代表论文的发表时间）