Single nucleotide polymorphism mapping of a barred plumage locus on chicken Z chromosome
Chicken sex-linked barred plumage locus was a dominant locus on chicken Z chromosome. The locus could be utilized to produce phenotypes that identify the sexes of chicks at hatching without crossing in pure line chicken production. But the locus mapping lagged behind the sex-linked silver feather locus and the sex-linked slow feathering locus. Here 28 single nucleotide polymorphisms on chicken Z chromosome were genotyped and made use of association study with barred plumage locus. The results showed certain single nucleotide polymorphism (CZ23) at 52148321 bp on Z chromosome was high significantly associated with barred plumage phenotype. The useful extent of linkage disequilibrium was around 1 Mb in the experimental chicken population. Thus a barred plumage locus was in the region from 51.1 Mb to 53.1 Mb. Bioinformatics analyses indicated that CZ23 existed in the twelfth intron of LOC427290 gene. The three genes, LOC427290, LOC769710 and LOC427291, were predicted as candidate genes for sex-linked barred plumage phenotype.
染色体 单核苷酸多态性 基因多态性 养鸡技术
Chenglong Luo Jian Lin Qinghua Nie Guanfu Yang Xiquan Zhang
College of Animal Science,South China Agricultural University,Guangzhou 510642,Guangdong,China
国内会议
青岛
英文
724-732
2008-10-18（万方平台首次上网日期，不代表论文的发表时间）