Eztended surgical resection plus percutaneous isolated hepatic perfusion for multiple hepatocellular carcinoma with portal vein tumor thrombus
Complete removal of the tumor by either hepatectomyor liver transplantation currently represents theonly formof potentially curative treatment for hepatocellularcarcinoma(HCC).However,only 10 to 30%of patientspresentwith resectable tumors,and systemic chemotherapy ismarginally effective because the narrow therapeuticratio preeludes dose escalation.This situation has led us todevelop a novel alternative method of drug deliverywith percuta-neous isolated hepatic perfusion(PIHP).The techniqueavoids extensive surgical mobilization and dissectionof theliver to achieve a dose-intensified intraarterial chemotherapy.
肝癌 手术切除 肝脏隔离灌注 门静脉栓
Yonson Ku(具英成)
Department of Surgery,kobe University Graduate School of Medicine
国内会议
中国医师协会外科医师分会成立大会暨第十二届全国普通外科学术会议
上海
英文
1-5
2007-11-16(万方平台首次上网日期,不代表论文的发表时间)