A New Non-Viral Vector Assemblies of LMw polyethylenimine cross-linked by β-cyclodeztrin for DNA delivery

摘要：

A critical stumbling block to the routineclinical implementation of human gene therapy isthe need for efficient and safe methods for genedelivery. While recombinant viruses are the mostefficient gene delivery vectors currently available,polymeric vectors have several advantages thatmake them a promising alternative. The development ofpolyplexes for gene delivery has grownrapidly to include cationic polymers such as poly-L-lysine(PLL), polyethylenmine(PEI), chitosan,pAMAM,dendrimers and many other polycation.

关键词： 非病毒载体 聚乙烯亚胺 β环糊精 基因治疗 壳聚糖

作者: Tang GuPing

作者单位: College of Science,Zhejiang University,Hangzhou,310031

会议类型: 国内会议

会议名称: 首届长三角科技论坛：长三角生物医药发展论坛

会议地点: 杭州

会议语种:英文

页码: 16-17

在线出版日期: 2004-10-01（万方平台首次上网日期，不代表论文的发表时间）