Preoperative endoscopic cryotherapy plus surgery for the treatment of esophageal cancer
Objective To investigate whether preoperative freezing plus traditional operative resection would improve 5-year survival rate of patients with esophageal cancer.Methods 50 patients admitted for esophageal cancer were divided equally at random.The treatment group(n=25)received cryotherapy before traditional surgery. The rest, without pretreatment, had surgery as control.Their one,three,fire-year survival rate were compared. Results With pretreatment 1,3,5-year survival ratereached92,76,and 56 percent respectively,while that of the controls attained 80,40,and 28percent accordingly.Statistically significant difference in survival did exist between groups by the end of 3 and 5 years after the combined therapy,yet no difference was detected within 1 year.Conclusion Preoperative cryotherapy could reduce the possibility of lymphatic metastasis,iatrogenic spread during operation and improve patient”s immunological functions life span.
Esophageal cancer Cryotherapy Preoperative
Rui-Sen Yang Hong-bo Guo Shu-Guang Liu Bai-Jiang Zhang Hui Li Xi-Bin Liu
Department of Thoracic Surgery,Shandong Tumor Hospital,Ji”nan 250117,P.R.China
国内会议
广州
英文
114-118
2008-05-16(万方平台首次上网日期,不代表论文的发表时间)