The Study on the Cardioprotective Effects of Diazoxide on the Myocardial Ischemia/Reperfusion Injury of Rats

摘要：

Mitochondrial ATP-sensitive K+ channels(mito KATP)have been shown to be one of the important protective mechanisms for myocardium undergoing ischemia/reperfusion. Diazoxide，the mito KATP opener，is likely to be involved in the cardioprotective effects of ischaemic preconditioning in reducing lactate dehydrogenase release and improvement in heart function. In our study，we investigated the cardioprotective effects and mechanisms of diazoxide on the myocardial ischemia/reperfusion unjury of rats.

关键词： 心肌局部缺血 再灌注损伤 缺血再灌注

作者: Yang Yunhai Zhao Jing Hu Zhiwei Yang Yunhai Ni Yiming

作者单位: Department of Cardiovascular Surgery the First Affiliated Hospital; Medical College; Zhejiang Unirer Department of Cardiovascular Surgery, Union Hospital, Tongji Medical college,Huazhong University of

会议类型: 国内会议

会议名称: 2006年浙江省医学会胸心外科学年会

会议地点: 浙江台州

会议语种:英文

在线出版日期: 2006-11-01（万方平台首次上网日期，不代表论文的发表时间）