The clinical value of exhaled nitric oxide in patients with lung cancer

摘要：

　　Introduction and Objectives: To investigate the clinical value of fractional exhaled nitric oxide(FeNO)in lung cancer patients.Methods: A total of 172 healthy control subjects and 164 patients with histopathologically confirmed lung cancer were enrolled in this study.FeNO measurements,pulmonary function tests and the baseline information were conducted.Results: The patients with lung cancer had a significantly higher level of eNO than the healthy control subjects(33.85±15.63 ppb,n=163; 16.83±4.17 ppb,n=172; p<0.01).The areas under receiver operating characteristic curves(AUC)for eNO predicting airway inflammation in lung cancer subjects and healthy control subjects was 0.932(95%CI: 0.904–0.961).The eNO levels in different types of lung cancer were significantly different.Conclusions: The eNO levels in patients with lung cancer were higher than the normal level.Measuring eNO will be helpful in diagnosing airway inflammation in lung cancer and in the classification of lung cancer.

关键词： exhaled nitric oxide (eNO) lung cancer airway inflammation pulmonary function

作者: 刘鹏飞

作者单位: 解放军总医院;武警后勤学院附属医院

会议类型: 国内会议

会议名称: 2017中华医学会呼吸病学年会暨第十八次全国呼吸病学学术会议

会议地点: 福州

会议语种:英文

页码: 1-1

在线出版日期: 2017-09-20（万方平台首次上网日期，不代表论文的发表时间）