Exploration of Toxicity Identification Evaluation Method to Characterize Metal Toxicity on Aging in a Paper Recycling Mill Using Nematode Caenorhabditis elegans
Toxicity Identification Evaluation (TIE) can be used to determine the specific toxicant(s) in marine effluents and sediments. In the current work, we attempted to combine the advantages of model organism, Caenorhabditis elegans, with the virtues of TIE technique to evaluate and identify the metal toxicity on aging from a paper recycling mill. Our results suggested that only the toxicity from MC filtration and EDTA treatment was similar to the baseline aging toxicity in TIE assay. Examine of the accumulation of intestinal autofluorescence in adult animals further confirmed that the short lifespans were actually due to accelerated aging. In addition, exposure to fractions of EDTA manipulations couldnt result in severe defects of reproduction and locomotion behaviors in C. elegans. Our work here provided a new thoughtfulness for evaluating environmental risk and identifying toxicant(s) from marine effluent or even sediments.
metals aging toxicity identification evaluation (TIE) C. elegans
WANG Yang WANG Xiaoyi SHEN Lulu YU Hongxia WANG Dayong
Department of Genetics and Developmental Biology, Southeast University, Nanjing 210009, Jiangsu, Chi State Key Laboratory of Pollution Control and Resource Reuse, School of the Environment, Nanjing Uni
国际会议
2007环境科学与技术国际会议(The 2007 International Symposium on Environmental Science and Technology)
北京
英文
2007-11-13（万方平台首次上网日期，不代表论文的发表时间）